Sterilization & Disinfection Hospitals by MVX

MVX Fighting H5N1 Bird Flu ( avian flu )

• Nanotechnology & Sterilization 

• Nosocomial Infection .

• Titanium dioxide TiO2

• What is photo catalyst  TiO2

• Mechanism of action  " MVX " for Sterilization

• Functions of Sterilization " MVX "

• MVX " Antiviral effect ( avian flu )

• MVX Anti Fungal Effect

• MVX Anti Dirt Effect

• Quality & Safety

Nanotechnology and sterilization of hospitals

It's the revolutionary science and art of manipulating matter at the atomic
 or molecular scale. The objective of nanotechnology is to produce
materials of special function with new physical & chemical properties
by making atoms & molecules behave differently.

Nanotechnology is considered to be one of the most important sites of investment funded by the governorates, and here are some examples for the fund of pioneers in nanotechnology.

Nanotechnology was our gate to reach a new material; it's old in reality but with this new technology we have changed lots of its properties; it's titanium dioxide TiO2

Nosocomial Infection

Although Nosocomial infections have been recognized since more over than 150 years but they remain a hazard to both health workers & patients.  Infection control has become a formal discipline in the United States since the 1950s due to the spread of staphylococcal infections in hospitals. Today Nosocomial infections accounts for 50% of all major complications of hospitalization. In 1974 only 2% of staphylococcus aurous infections can't be cured with commonly used antibiotics. By 2003, that figure had reached 57% and is still rising. The cause is that microbes existing in environment where antibiotics are constantly used are likely to develop a resistance to most of these antibiotics in use

And stated sites of infection are:
So, we are facing a real problem which is that disinfection systems can't meet the recommended degree of disinfection by far especially in the developing countries. And that's why Japanese scientists don't stop studies for reaching solutions for the problem especially with the introduction of nanotechnology Nanotechnology & Sterilization

Titanium dioxide TIO2

TiO2 is a white powder, used extensively in many commercial products including paints, plastics, paper, food & cosmetic products. TiO2 is insoluble in water & sensitive as a photo catalyst to certain wave length of ultraviolet light, nanotechnology had changed its characteristics, dissolved it in water & made it sensitive to any source of light. So it can be used as a photo catalyst when exposed to any source of light.

What is photo catalyst ?

It is a material which is sensitive to light excited and makes a chemical reaction when light strikes it. For example, chlorophyll in green plants is a photo catalytic material begins a chemical reaction when exposed to light.

TiO2 photo catalysis

Our new titanium dioxide " MVX " when stroked by light a chemical reaction will begin causing the breakdown of organic toxins, odors & moreover.

Mechanism of action for " MVX " Sterilization

(A) At the level of radicals

When light strikes "MVX" this produces two oxidation reactants, hydroxyl radicals (OH-) & super oxide anion (O2-). The two reactants decompose toxic organic substances through oxidation. The light source only begins the reaction & it keeps working for several hours even after the light source is cut

(B) At the level of molecules:

The nucleus of an atom is surrounded by orbits where electrons are revolving around the nucleus. Electrons responsible for reactions are revolving in a band called valence band.

There is a band outside the valence band referred to as the conduction band.

In TiO2, as it is a compound consisting of different atoms, the valence and conduction bands are complicated, but the principles involved are the same. When the energy of light is applied externally electrons in the valence band are excited and rise to the conduction band. Then positive holes are formed and left behind the rising electrons in the valence band. At this time the MVX is photo excited. The resulting positive holes show sufficient oxidative power.

As MVX is TiO2 dissolved in water, water is oxidized by positive holes forming hydroxyl radicals (OH-) which has a strong oxidative decomposing power.

Also, Oxygen of the air is reduced by the rising electrons resulting in the production of super oxide anions (O2-) which is capable of attacking bacteria. Both super oxide anion and hydroxyl radicals are the main reactants responsible for the functions of MVX.

Functions of Sterilization " MVX "

1) Antibacterial & Detoxification Action

MVX has excellent bactericidal effects even without ultra violet rays, furthermore, when U.V. rays are irradiated,  MVX also can decompose the remnants of dead bacteria.

(A)Test Results

(B)MIC Minimum Inhibitory Concentration

The antibacterial Performance standard established by the society of industrial technology for antimicrobial articles (SIAA) in Japan is 800 µgm/ml or less, MVX is certified to have an antibacterial effect, the measured MIC values for different types of bacteria shown in the table.

Testing organizations
1- Microbiology laboratory, Faculty of pharmacy, Meijo university in Japan.
2- Japan food Research laboratories.

MVX Antiviral effect avian flu

MVX has strong effect on killing almost all kinds of viruses including SARS & Avian flu ( H5N1 ).

Effect against influenza viruses

The amount of antibodies in normal blood uninfected by viruses is approximately 2 µgm/ml which was   defined as HA value = 2, when blood is infected by a virus, hem agglutinin occurs, causing antibodies to increase in number. The HA value of 1280 for the untreated samples means that the virus caused heamgglutination and increased the number of antibodies by 640 times.

-On the other hand, the samples treated with the MVX inhibited heamagglutination by destroying the virus.

N.B the numerical values are HA values (n=3) measured after 24 hours of contact.
(#) Mark: indicates that hem agglutination was not observed.
Sample virus: influenza virus AOPR8
Testing organization: Kitasato Research center of environmental sciences.

MVX " Anti Fungal Effect

MVX has a good antifungal effect on different types of fungi e.g. Aspergillums Niger & Candida albicans reducing their concentration by 34.65% after 2 hours of contact.

MVX Deodorizing Effect

MVX produces a noticeable difference in deodorizing character. The smell of very high concentrations of ammonia gases (40 ppm) in a 2 hour period will dissipate up to 99.6%.

MVX Anti Dirt Effect

MVX gives relative charges to the surface it's coated with when exposed to every source of light, also fine dust carries negative charges so, both the surface & the dust carry negative charge and they repel with each other so, surface clear without accumulation of dust.

MVX Hydrophilic effect

M character due to the presence of (OH-) radicals, with very high affinity to water, and self cleaning effect is generated by waterfall.

THE ACTIVITY OF " MVX  "

MVX produces long lasting disinfection remains for 5 years and certainly we have a very good visible proof for the validity of MVX functions as a sterilizing material for surfaces. As we have known that the mechanism of action of MVX depends on the presence of (OH-) & (O2-) radicals.

So, we have 2 tests ensuring the presence of these two radicals.

(1) Silver nitrate : is a colorless solution turns black in color due to the presence of O2- radicals .
(2) Methelene blue : is a blue colored liquid when oxidized, its color fades within 30 minutes due to the presence of (OH-) radicals.

At the start of the test	After 30 minutes	After 90 minutes

Mold resistance test
( 1 ) Aspergillus niger
                 Black yeast mold – drying matrix; fiber, industrial product.
( 2 ) Penicillium citrinum
                 Blue mold – resistant to drying; propagates in general houses.
( 3 ) Rhizopus oryzae
                Spider web mold ( Kumonosu kabi ) general foods.
( 4 ) Cladosporium / cladosporioides
         Black scale mold ( Kurokawa kabi ) – propagates in humid places such as a bathroom and washroom
( 5 ) Chaetomium globosum
               “ Ketana kabi “ mold – resistant to coldness; propagates on silk, jute and paper